Publications

Peer-reviewed journal publications

Bayer, J.D, Sobota, V., Bear, L.R., Haïssaguerre, M., Vigmond, E.J. A His bundle pacing protocol for suppressing ventricular arrhythmia maintenance and improving defibrillation efficacy. Computer Methods and Programs in Biomedicine, 2024.

van Hunnik*, A., Sobota*, V., Zeemering, S., Opacic, D., Scaf, B., D'Alessandro, E., Oyaert, K., Kuiper, M., Diness, J.G., Sørensen, U.S., Milnes J.T., van der Heyden, M.A., Jespersen, T., Schotten, U., Verheule, S. Analysis of drug-induced and spontaneous cardioversions reveals similar patterns leading to termination of atrial fibrillation. Frontiers in Physiology, 2024.

Fernández, D.I., Troitiño, S., Sobota, V., Tullemans, B.M.E., Zou, J., van den Hurk, H., García, Á., Hornanejad, S., Kuijpers, M.J.E., Heemskerk, J.W.M. Ultra-high throughput screening for the discovery of antiplatelet drugs affecting receptor dependent calcium signaling dynamics. Scientific Reports, 2024.

Ramadan, A., Chleilat, E., Martinez-Navarro, H., Brennan-McLean, J., Copier, J., Caldwell, J., Greiner, J., Martínez Díaz, P., Sobota, V. Gordon research conference on cardiac arrhythmia mechanisms 2023: early career investigators' views on emerging concepts and technologies. The Journal of Physiology, 2023.

Bayer, J.D., Sobota, V., Moreno, A., Jaïs, P., Vigmond, E. J. The Purkinje network plays a major role in low-energy ventricular defibrillation. Computers in Biology and Medicine, 2022.

Gatta, G., Sobota, V., Citerni, C., Dines, J.G. Sørensen, U.S., Jespersen, T., Bentzen, B.H., Zeemering, S., Kuiper, M., Verheule, S. Schotten, U. van Hunnik, A. Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction. Europace, 2021.

Sobota, V., Gatta, G., van Hunnik, A., van Tuijn, I. Kuiper, M., Milnes, J., Jespersen, T. Schotten, U. Verheule, S. The acetylcholine-activated potassium current inhibitor XAF-1407 terminates persistent atrial fibrillation in goats. Frontiers in Pharmacology, 2021.

Gharaviri, A., Pezzuto, S. Potse, M. Conte, G. Zeemering, S. Sobota, V. Verheule, S. Krause, R., Auricchio, A., Schotten, U. Synergistic antiarrhythmic effect of inward rectifier current inhibition and pulmonary vein isolation in a 3D computer model of atrial fibrillation. Europace, 2021.

Sobota, V., Müller, M., Roubík, K. Intravenous administration of normal saline may be misinterpreted as a change of end-expiratory lung volume when using electrical impedance tomography. Scientific Reports, 2019.

Conference papers

Sobota, V., Nordmeyer, S., Augustin, C.M., Plank, G., Vigmond, E.J., Bayer J.D. Method for incorporating changes in extracellular volume and myocyte size into cardiac bidomain equations. Computing in Cardiology 2022, Tampere, Finland.

Sobota, V., Langer, M. Regional time constants determined by electrical impedance tomography are affected by ventilatory parameters. 20th International Student Conference on Electrical Engineering POSTER 2016.

Sobota, V., Roubík, K. Center of ventilation – methods of calculation using electrical impedance tomography and the influence of image segmentation. XIV Mediterranean Conference on Medical and Biological Engineering and Computing (MEDICON), 2016.

Roubík, K., Sobota, V., Laviola, M. Selection of the baseline frame for evaluation of electrical impedance tomography of the lungs. The 2nd International Conference on Mathematics and Computers in Science and Industry (MCSI), 2015.

Masopustová, M., Sobota, V., Marešová, Z., Ráfl, J., Rožánek, M. Changes of the electrode plain position within the recommended area affect significantly the results of ventilation analysis using EIT. The 6th International Young Biomedical Engineers and Researchers Conference (YBERC), 2014.

Sobota, V., Suchomel, J. Monitoring of pulmonary embolism using electrical impedance tomography: A case study. E-health and Bioengineering Conference (EHB), 2013.

Suchomel, J., Sobota, V. A model of end-expiratory lung impedance dependency on total extracellular body water. Journal of Physics: Conference Series, vol. 434, 2013.

Conference abstracts (selected)

Sobota, V., Stoks, J., Shetty, R., Ni, H., Grandi, E., Ng, F.S., Volders, P.G.A., Cluitmans, M.J.M., Bayer J.D. Age-associated changes in the apicobasal repolarization gradient affect arrhythmia vulnerability in the human ventricles. Cardiac Physiome Workshop 2024, Freiburg im Breisgau, Germany.

Sobota, V., Augustin, C.M., Vigmond, E.J., Nordmeyer, S., Bayer J.D. Increased extracellular volume in the ventricles after aortic valve replacement is not associated with decreased conduction velocity: a computational study. Czech Cardiovascular Research and Innovation Days 2023, Prague, Czech Republic.

Sobota, V., Augustin, C.M., Nordmeyer, S., Vigmond, E.J., Bayer J.D. Regional differences in extracellular volume increase arrhythmia vulnerability in aortic stenosis patients with and without diffuse fibrosis: a computational study. European Society of Cardiology Congress 2023, Amsterdam, The Netherlands.

Sobota, V., Augustin, C.M., Nordmeyer, S., Vigmond, E.J., Bayer J.D. Overall fibrosis content rather than regional differences in extracellular volume alters ventricular conduction in aortic stenosis patients. European Heart Rhythm Association (EHRA) Congress 2023, Barcelona, Spain.

Sobota, V., Prassl, A.J., Ozenne, V. Augustin, C.M., Nordmeyer, S., Bayer J.D. Cardiac remodelling due to aortic stenosis increases vulnerability to ventricular arrhythmias: an insight from computational models. ERA-CVD Symposium 2022, Riga, Latvia.

Sobota, V., Prassl, A.J., Ozenne, V. Augustin, C.M., Nordmeyer, S., Bayer J.D. The interplay of sex-specific electrophysiology and repolarization heterogeneity governs ventricular arrhythmia sustainability in women. European Society of Cardiology Congress 2022, Barcelona, Spain.

Sobota, V., van Hunnik, A., Zeemering, S., Gatta, G., Opacic, D., Scaf, B., D'Alessandro, E., Oyaert, K., Dines, J.G., Sørensen, U.S., van der Heyden, M.A.G., Schotten, U., Verheule, S. Termination of atrial fibrillation during pharmacological cardioversion in the goat requires inter-atrial synchronization of conduction. European Heart Rhythm Association (EHRA) Congress 2021.

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